| Game Results | ||
| Teams | Date | Score |
| East Rock at Dunedin | 9/12/2010 | DUN 48-34 |
| Orange County at Woodbridge | 9/12/2010 | WOO 27-24 |
| St. Paul at Bloomington | 9/12/2010 | BLF 24-12 |
| Blackburn at Buffalo | 9/12/2010 | BUF 35-14 |
| Summit City at Iowa | 9/12/2010 | SCT 17-10 |
| Las Vegas at Mesa | 9/12/2010 | MRR 20-19 |
| Visitation at Jersey | 9/12/2010 | JER 45-14 |
| Los Angeles at Dallas | 9/12/2010 | LAK 34-32 |
| Mercer at London | 9/12/2010 | MER 34-13 |
| Minnesota at Rocky Mountain | 9/12/2010 | MIN 31-16 |
| Baltimore at Florida | 9/12/2010 | FGC 23-6 |
| Dracut at Big Grove | 9/12/2010 | DRA 37-7 |
| Big Grove at Dunedin | 9/19/2010 | DUN 52-24 |
| Dracut at East Rock | 9/19/2010 | ERR 36-13 |
| Woodbridge at Bloomington | 9/19/2010 | WOO 24-6 |
| Orange County at St. Paul | 9/19/2010 | OCJ 27-26 |
| Buffalo at Iowa | 9/19/2010 | IOW 33-19 |
| Blackburn at Summit City | 9/19/2010 | BLA 31-14 |
| Mesa at Jersey | 9/19/2010 | JER 30-15 |
| Las Vegas at Visitation | 9/19/2010 | LAS 33-3 |
| Dallas at London | 9/19/2010 | LON 24-21 |
| Los Angeles at Mercer | 9/19/2010 | LAK 41-33 |
| Rocky Mountain at Florida | 9/19/2010 | FGC 13-6 |
| Minnesota at Baltimore | 9/19/2010 | MIN 24-16 |
| East Rock at Big Grove | 9/26/2010 | BGB 38-23 |
| Bloomington at Orange County | 9/26/2010 | OCJ 41-3 |
| St. Paul at Woodbridge | 9/26/2010 | WOO 28-14 |
| Iowa at Blackburn | 9/26/2010 | IOW 34-17 |
| Summit City at Buffalo | 9/26/2010 | BUF 42-6 |
| Jersey at Las Vegas | 9/26/2010 | LAS 31-0 |
| Visitation at Mesa | 9/26/2010 | VIV 16-13 |
| London at Los Angeles | 9/26/2010 | LAK 30-16 |
| Mercer at Dallas | 9/26/2010 | MER 29-9 |
| Florida at Minnesota | 9/26/2010 | MIN 24-6 |
| Baltimore at Rocky Mountain | 9/26/2010 | BAL 34-24 |
| Dunedin at Dracut | 9/26/2010 | DRA 42-16 |
| Dallas at Big Grove | 10/3/2010 | BGB 31-14 |
| Baltimore at East Rock | 10/3/2010 | BAL 34-31 |
| Jersey at Dunedin | 10/3/2010 | DUN 24-10 |
| Los Angeles at Orange County | 10/3/2010 | LAK 27-26 |
| Rocky Mountain at Woodbridge | 10/3/2010 | WOO 24-17 |
| Las Vegas at Dracut | 10/3/2010 | DRA 27-3 |
| London at Bloomington | 10/3/2010 | BLF 34-24 |
| Minnesota at Blackburn | 10/3/2010 | BLA 24-10 |
| Mesa at Buffalo | 10/3/2010 | BUF 31-9 |
| Mercer at Summit City | 10/3/2010 | MER 28-10 |
| Florida at Iowa | 10/3/2010 | FGC 24-12 |
| Visitation at St. Paul | 10/3/2010 | STP 18-14 |
| Big Grove at Baltimore | 10/10/2010 | BGB 20-19 |
| East Rock at Jersey | 10/10/2010 | JER 30-18 |
| Dunedin at Las Vegas | 10/10/2010 | DUN 41-10 |
| Orange County at Rocky Mountain | 10/10/2010 | OCJ 31-21 |
| Woodbridge at Visitation | 10/10/2010 | WOO 59-14 |
| St. Paul at London | 10/10/2010 | LON 30-20 |
| Bloomington at Los Angeles | 10/10/2010 | LAK 45-18 |
| Blackburn at Mesa | 10/10/2010 | BLA 27-6 |
| Buffalo at Mercer | 10/10/2010 | BUF 31-23 |
| Summit City at Florida | 10/10/2010 | FGC 27-9 |
| Iowa at Minnesota | 10/10/2010 | MIN 43-7 |
| Dracut at Dallas | 10/10/2010 | DRA 48-28 |
| Jersey at Big Grove | 10/17/2010 | JER 20-13 |
| Las Vegas at East Rock | 10/17/2010 | ERR 23-17 |
| Dallas at Dunedin | 10/17/2010 | DUN 28-3 |
| Visitation at Orange County | 10/17/2010 | OCJ 55-0 |
| London at Woodbridge | 10/17/2010 | WOO 23-0 |
| Los Angeles at St. Paul | 10/17/2010 | STP 39-33 |
| Rocky Mountain at Bloomington | 10/17/2010 | RKY 35-31 |
| Mercer at Blackburn | 10/17/2010 | BLA 13-10 |
| Florida at Buffalo | 10/17/2010 | BUF 35-6 |
| Minnesota at Summit City | 10/17/2010 | MIN 37-27 |
| Mesa at Iowa | 10/17/2010 | MRR 21-18 |
| Baltimore at Dracut | 10/17/2010 | DRA 48-7 |
| Big Grove at Las Vegas | 10/24/2010 | LAS 30-21 |
| East Rock at Dallas | 10/24/2010 | ERR 31-20 |
| Dunedin at Baltimore | 10/24/2010 | DUN 42-21 |
| Orange County at London | 10/24/2010 | OCJ 20-3 |
| Woodbridge at Los Angeles | 10/24/2010 | LAK 40-21 |
| St. Paul at Rocky Mountain | 10/24/2010 | STP 37-23 |
| Bloomington at Visitation | 10/24/2010 | VIV 42-38 |
| Blackburn at Florida | 10/24/2010 | FGC 31-21 |
| Buffalo at Minnesota | 10/24/2010 | MIN 21-17 |
| Summit City at Mesa | 10/24/2010 | MRR 23-17 |
| Iowa at Mercer | 10/24/2010 | IOW 24-13 |
| Dracut at Jersey | 10/24/2010 | DRA 35-7 |
| Orange County at Dunedin | 10/31/2010 | DUN 33-30 |
| Blackburn at Bloomington | 10/31/2010 | BLA 34-24 |
| Big Grove at Summit City | 10/31/2010 | SCT 38-31 |
| Woodbridge at East Rock | 10/31/2010 | WOO 47-45 |
| Buffalo at St. Paul | 10/31/2010 | BUF 42-15 |
| Las Vegas at Florida | 10/31/2010 | LAS 30-6 |
| Los Angeles at Jersey | 10/31/2010 | LAK 29-26 |
| Minnesota at London | 10/31/2010 | MIN 28-10 |
| Mesa at Baltimore | 10/31/2010 | MRR 20-10 |
| Dallas at Visitation | 10/31/2010 | DAL 34-17 |
| Rocky Mountain at Mercer | 10/31/2010 | MER 18-13 |
| Dracut at Iowa | 10/31/2010 | DRA 52-3 |
| Dunedin at Blackburn | 11/7/2010 | BLA 30-6 |
| Iowa at Bloomington | 11/7/2010 | IOW 17-3 |
| Woodbridge at Big Grove | 11/7/2010 | WOO 34-24 |
| East Rock at Buffalo | 11/7/2010 | ERR 41-21 |
| Summit City at St. Paul | 11/7/2010 | STP 30-16 |
| Los Angeles at Las Vegas | 11/7/2010 | LAK 38-28 |
| Jersey at Minnesota | 11/7/2010 | MIN 28-24 |
| Florida at London | 11/7/2010 | LON 17-14 |
| Dallas at Mesa | 11/7/2010 | MRR 21-20 |
| Visitation at Rocky Mountain | 11/7/2010 | RKY 34-13 |
| Baltimore at Mercer | 11/7/2010 | MER 44-0 |
| Orange County at Dracut | 11/7/2010 | DRA 25-10 |
| Orange County at Summit City | 11/14/2010 | OCJ 28-10 |
| Blackburn at East Rock | 11/14/2010 | BLA 31-14 |
| Dunedin at Woodbridge | 11/14/2010 | WOO 34-20 |
| Bloomington at Buffalo | 11/14/2010 | BUF 49-18 |
| Iowa at Big Grove | 11/14/2010 | BGB 28-14 |
| Las Vegas at Mercer | 11/14/2010 | MER 36-24 |
| Los Angeles at Baltimore | 11/14/2010 | LAK 30-7 |
| Minnesota at Visitation | 11/14/2010 | MIN 38-0 |
| Jersey at Dallas | 11/14/2010 | JER 56-17 |
| London at Rocky Mountain | 11/14/2010 | RKY 31-19 |
| Florida at Mesa | 11/14/2010 | FGC 21-14 |
| Dracut at St. Paul | 11/14/2010 | DRA 43-3 |
| East Rock at Bloomington | 11/21/2010 | ERR 40-13 |
| St. Paul at Iowa | 11/21/2010 | IOW 28-19 |
| Summit City at Dunedin | 11/21/2010 | DUN 35-14 |
| Big Grove at Orange County | 11/21/2010 | OCJ 20-19 |
| Woodbridge at Blackburn | 11/21/2010 | WOO 26-24 |
| Buffalo at Dracut | 11/21/2010 | DRA 34-26 |
| Visitation at London | 11/21/2010 | VIV 35-24 |
| Baltimore at Jersey | 11/21/2010 | JER 30-13 |
| Mesa at Los Angeles | 11/21/2010 | LAK 35-11 |
| Dallas at Minnesota | 11/21/2010 | MIN 52-20 |
| Rocky Mountain at Las Vegas | 11/21/2010 | LAS 31-24 |
| Mercer at Florida | 11/21/2010 | MER 30-3 |
| Dracut at Blackburn | 11/28/2010 | DRA 20-10 |
| Iowa at Orange County | 11/28/2010 | OCJ 29-23 |
| Bloomington at Dunedin | 11/28/2010 | DUN 30-7 |
| Big Grove at Buffalo | 11/28/2010 | BUF 37-10 |
| Summit City at Woodbridge | 11/28/2010 | WOO 37-34 |
| St. Paul at East Rock | 11/28/2010 | ERR 31-20 |
| Las Vegas at Minnesota | 11/28/2010 | MIN 21-17 |
| Florida at Los Angeles | 11/28/2010 | LAK 38-10 |
| London at Jersey | 11/28/2010 | JER 13-10 |
| Mesa at Rocky Mountain | 11/28/2010 | RKY 33-17 |
| Baltimore at Dallas | 11/28/2010 | DAL 34-31 |
| Mercer at Visitation | 11/28/2010 | MER 34-9 |
| Blackburn at Orange County | 12/5/2010 | OCJ 27-10 |
| Dunedin at Iowa | 12/5/2010 | DUN 48-7 |
| Buffalo at Woodbridge | 12/5/2010 | BUF 35-31 |
| St. Paul at Big Grove | 12/5/2010 | STP 42-36 |
| East Rock at Summit City | 12/5/2010 | ERR 27-24 |
| Minnesota at Los Angeles | 12/5/2010 | MIN 23-20 |
| London at Las Vegas | 12/5/2010 | LAS 35-20 |
| Jersey at Florida | 12/5/2010 | JER 35-21 |
| Rocky Mountain at Dallas | 12/5/2010 | RKY 28-24 |
| Mercer at Mesa | 12/5/2010 | MRR 37-30 |
| Bloomington at Dracut | 12/5/2010 | DRA 48-7 |
| Visitation at Baltimore | 12/5/2010 | VIV 30-24 |
| Woodbridge at Orange County | 12/12/2010 | WOO 24-10 |
| Bloomington at St. Paul | 12/12/2010 | BLF 27-24 |
| Buffalo at Blackburn | 12/12/2010 | BUF 21-0 |
| Iowa at Summit City | 12/12/2010 | SCT 45-24 |
| Mesa at Las Vegas | 12/12/2010 | LAS 13-6 |
| Jersey at Visitation | 12/12/2010 | JER 21-16 |
| Dallas at Los Angeles | 12/12/2010 | LAK 41-6 |
| London at Mercer | 12/12/2010 | MER 23-20 |
| Rocky Mountain at Minnesota | 12/12/2010 | MIN 41-16 |
| Florida at Baltimore | 12/12/2010 | FGC 28-7 |
| Big Grove at Dracut | 12/12/2010 | DRA 55-24 |
| Dunedin at East Rock | 12/12/2010 | DUN 41-38 |
| Bloomington at Woodbridge | 12/19/2010 | WOO 45-10 |
| St. Paul at Orange County | 12/19/2010 | OCJ 31-11 |
| Iowa at Buffalo | 12/19/2010 | BUF 33-3 |
| Summit City at Blackburn | 12/19/2010 | BLA 23-20 |
| Jersey at Mesa | 12/19/2010 | JER 16-13 |
| Visitation at Las Vegas | 12/19/2010 | LAS 35-7 |
| London at Dallas | 12/19/2010 | DAL 24-10 |
| Mercer at Los Angeles | 12/19/2010 | LAK 45-15 |
| Florida at Rocky Mountain | 12/19/2010 | RKY 34-28 |
| Baltimore at Minnesota | 12/19/2010 | MIN 48-13 |
| East Rock at Dracut | 12/19/2010 | DRA 45-27 |
| Dunedin at Big Grove | 12/19/2010 | DUN 26-10 |
| Dracut at Dunedin | 12/26/2010 | DRA 45-9 |
| Big Grove at East Rock | 12/26/2010 | BGB 35-30 |
| Blackburn at Iowa | 12/26/2010 | BLA 30-0 |
| Buffalo at Summit City | 12/26/2010 | BUF 24-18 |
| Las Vegas at Jersey | 12/26/2010 | LAS 40-10 |
| Mesa at Visitation | 12/26/2010 | MRR 28-12 |
| Los Angeles at London | 12/26/2010 | LAK 41-7 |
| Dallas at Mercer | 12/26/2010 | MER 27-14 |
| Minnesota at Florida | 12/26/2010 | MIN 34-20 |
| Rocky Mountain at Baltimore | 12/26/2010 | RKY 34-10 |
| Orange County at Bloomington | 12/26/2010 | OCJ 30-10 |
| Woodbridge at St. Paul | 12/26/2010 | WOO 38-17 |