| Game Results |
| Teams | Date | Score |
| Chicago B at Green Bay | 9/28/1958 | CHN 24-13 |
| Cleveland at Los Angeles | 9/28/1958 | CLN 38-24 |
| Detroit at Baltimore | 9/28/1958 | BAN 17-14 |
| New York at Chicago C | 9/28/1958 | CCN 9-6 |
| Pittsburgh at San Francisco | 9/28/1958 | PIN 24-22 |
| Washington at Philadelphia | 9/28/1958 | PHN 26-24 |
| Chicago B at Baltimore | 10/4/1958 | BAN 30-27 |
| Washington at Chicago C | 10/4/1958 | WAN 34-34 |
| Cleveland at Pittsburgh | 10/5/1958 | PIN 31-24 |
| Detroit at Green Bay | 10/5/1958 | GBN 24-10 |
| New York at Philadelphia | 10/5/1958 | NYN 17-3 |
| Los Angeles at San Francisco | 10/5/1958 | LAN 41-14 |
| Baltimore at Green Bay | 10/12/1958 | BAN 31-6 |
| Chicago C at Cleveland | 10/12/1958 | CLN 35-7 |
| New York at Washington | 10/12/1958 | WAN 17-10 |
| Philadelphia at Pittsburgh | 10/12/1958 | PIN 34-21 |
| Los Angeles at Detroit | 10/12/1958 | DEN 37-24 |
| San Francisco at Chicago B | 10/12/1958 | CHN 23-9 |
| Baltimore at Detroit | 10/19/1958 | BAN 42-35 |
| Chicago C at New York | 10/19/1958 | NYN 40-14 |
| Green Bay at Washington | 10/19/1958 | WAN 35-14 |
| Pittsburgh at Cleveland | 10/19/1958 | CLN 21-13 |
| Los Angeles at Chicago B | 10/19/1958 | CHN 40-14 |
| San Francisco at Philadelphia | 10/19/1958 | PHN 31-7 |
| Chicago B at San Francisco | 10/26/1958 | CHN 21-17 |
| Cleveland at Chicago C | 10/26/1958 | CLN 27-14 |
| Detroit at Los Angeles | 10/26/1958 | LAN 24-10 |
| Philadelphia at Green Bay | 10/26/1958 | GBN 26-24 |
| Pittsburgh at New York | 10/26/1958 | NYN 30-6 |
| Washington at Baltimore | 10/26/1958 | BAN 26-10 |
| Chicago B at Los Angeles | 11/2/1958 | CHN 31-24 |
| Detroit at San Francisco | 11/2/1958 | DEN 40-19 |
| Green Bay at Baltimore | 11/2/1958 | BAN 45-7 |
| New York at Cleveland | 11/2/1958 | NYN 17-14 |
| Philadelphia at Chicago C | 11/2/1958 | PHN 27-27 |
| Washington at Pittsburgh | 11/2/1958 | PIN 35-34 |
| Baltimore at New York | 11/9/1958 | BAN 45-26 |
| Chicago C at Washington | 11/9/1958 | CCN 7-7 |
| Detroit at Cleveland | 11/9/1958 | CLN 31-10 |
| Green Bay at Chicago B | 11/9/1958 | GBN 17-17 |
| Pittsburgh at Philadelphia | 11/9/1958 | PHN 42-24 |
| San Francisco at Los Angeles | 11/9/1958 | LAN 28-15 |
| Baltimore at Chicago B | 11/16/1958 | BAN 21-9 |
| Chicago C at Philadelphia | 11/16/1958 | PHN 28-25 |
| Cleveland at Washington | 11/16/1958 | CLN 28-20 |
| New York at Pittsburgh | 11/16/1958 | NYN 24-24 |
| Los Angeles at Green Bay | 11/16/1958 | LAN 28-24 |
| San Francisco at Detroit | 11/16/1958 | DEN 12-0 |
| Chicago B at Detroit | 11/23/1958 | CHN 17-13 |
| Philadelphia at Cleveland | 11/23/1958 | CLN 34-23 |
| Pittsburgh at Chicago C | 11/23/1958 | CCN 34-17 |
| Los Angeles at Baltimore | 11/23/1958 | BAN 38-14 |
| San Francisco at Green Bay | 11/23/1958 | SFN 45-6 |
| Washington at New York | 11/23/1958 | WAN 16-16 |
| Green Bay at Detroit | 11/27/1958 | DEN 21-3 |
| Chicago B at Pittsburgh | 11/30/1958 | PIN 24-13 |
| Philadelphia at New York | 11/30/1958 | PHN 14-6 |
| Los Angeles at Chicago C | 11/30/1958 | CCN 37-20 |
| San Francisco at Baltimore | 11/30/1958 | BAN 38-20 |
| Washington at Cleveland | 11/30/1958 | WAN 31-22 |
| Baltimore at Los Angeles | 12/6/1958 | BAN 24-13 |
| Chicago C at Chicago B | 12/7/1958 | CHN 27-20 |
| Cleveland at Philadelphia | 12/7/1958 | CLN 21-7 |
| Green Bay at San Francisco | 12/7/1958 | GBN 23-13 |
| New York at Detroit | 12/7/1958 | NYN 16-13 |
| Pittsburgh at Washington | 12/7/1958 | WAN 27-24 |
| Chicago C at Pittsburgh | 12/13/1958 | PIN 44-0 |
| Baltimore at San Francisco | 12/14/1958 | BAN 58-17 |
| Cleveland at New York | 12/14/1958 | CLN 20-0 |
| Detroit at Chicago B | 12/14/1958 | DEN 28-3 |
| Green Bay at Los Angeles | 12/14/1958 | LAN 31-24 |
| Philadelphia at Washington | 12/14/1958 | PHN 24-21 |