| Game Results |
| Teams | Date | Score |
| Dallas at Buffalo | 9/19/1971 | DAN 23-7 |
| Houston at Cleveland | 9/19/1971 | CLA 26-3 |
| Kansas City at San Diego | 9/19/1971 | KCA 48-0 |
| Miami at Denver | 9/19/1971 | MIA 24-10 |
| New York NFC at Green Bay | 9/19/1971 | NYN 17-10 |
| New York AFC at Baltimore | 9/19/1971 | BAA 33-7 |
| Oakland at New England | 9/19/1971 | OAA 16-10 |
| Philadelphia at Cincinnati | 9/19/1971 | PHN 28-17 |
| Pittsburgh at Chicago | 9/19/1971 | PIA 34-21 |
| Los Angeles at New Orleans | 9/19/1971 | LAN 31-17 |
| San Francisco at Atlanta | 9/19/1971 | SFN 28-17 |
| Washington at St. Louis | 9/19/1971 | SLN 34-7 |
| Minnesota at Detroit | 9/20/1971 | MNN 17-6 |
| Atlanta at Los Angeles | 9/26/1971 | ATN 17-17 |
| Chicago at Minnesota | 9/26/1971 | MNN 21-20 |
| Cincinnati at Pittsburgh | 9/26/1971 | PIA 24-12 |
| Cleveland at Baltimore | 9/26/1971 | CLA 30-21 |
| Dallas at Philadelphia | 9/26/1971 | PHN 14-13 |
| Denver at Green Bay | 9/26/1971 | GBN 30-10 |
| Detroit at New England | 9/26/1971 | DEN 26-20 |
| Kansas City at Houston | 9/26/1971 | KCA 28-15 |
| Miami at Buffalo | 9/26/1971 | MIA 41-17 |
| Oakland at San Diego | 9/26/1971 | SDA 13-10 |
| San Francisco at New Orleans | 9/26/1971 | NON 31-9 |
| Washington at New York NFC | 9/26/1971 | WAN 10-6 |
| New York AFC at St. Louis | 9/27/1971 | NYA 17-16 |
| Atlanta at Detroit | 10/3/1971 | ATN 23-20 |
| Baltimore at New England | 10/3/1971 | BAA 23-16 |
| Buffalo at Minnesota | 10/3/1971 | MNN 29-13 |
| Chicago at Los Angeles | 10/3/1971 | LAN 31-14 |
| Cincinnati at Green Bay | 10/3/1971 | CNA 27-17 |
| Kansas City at Denver | 10/3/1971 | KCA 24-10 |
| New Orleans at Houston | 10/3/1971 | NON 24-23 |
| New York NFC at St. Louis | 10/3/1971 | NYN 10-7 |
| New York AFC at Miami | 10/3/1971 | MIA 38-17 |
| San Diego at Pittsburgh | 10/3/1971 | SDA 31-17 |
| San Francisco at Philadelphia | 10/3/1971 | PHN 27-10 |
| Washington at Dallas | 10/3/1971 | DAN 22-13 |
| Oakland at Cleveland | 10/4/1971 | OAA 14-13 |
| Baltimore at Buffalo | 10/10/1971 | BAA 23-10 |
| Green Bay at Detroit | 10/10/1971 | DEN 28-24 |
| Houston at Washington | 10/10/1971 | WAN 23-3 |
| Miami at Cincinnati | 10/10/1971 | MIA 21-20 |
| Minnesota at Philadelphia | 10/10/1971 | MNN 13-6 |
| New Orleans at Chicago | 10/10/1971 | NON 30-7 |
| New York AFC at New England | 10/10/1971 | NYA 14-12 |
| Oakland at Denver | 10/10/1971 | DEA 30-28 |
| Pittsburgh at Cleveland | 10/10/1971 | CLA 14-7 |
| Los Angeles at San Francisco | 10/10/1971 | SFN 27-24 |
| San Diego at Kansas City | 10/10/1971 | SDA 34-24 |
| St. Louis at Atlanta | 10/10/1971 | SLN 23-13 |
| New York NFC at Dallas | 10/11/1971 | DAN 30-14 |
| Baltimore at New York NFC | 10/17/1971 | NYN 25-20 |
| Buffalo at New York AFC | 10/17/1971 | BUA 24-24 |
| Chicago at San Francisco | 10/17/1971 | SFN 38-0 |
| Cleveland at Cincinnati | 10/17/1971 | CLA 17-16 |
| Dallas at New Orleans | 10/17/1971 | DAN 21-17 |
| Detroit at Houston | 10/17/1971 | HOA 31-27 |
| Minnesota at Green Bay | 10/17/1971 | MNN 13-3 |
| New England at Miami | 10/17/1971 | MIA 31-3 |
| Philadelphia at Oakland | 10/17/1971 | OAA 17-6 |
| Los Angeles at Atlanta | 10/17/1971 | LAN 23-3 |
| San Diego at Denver | 10/17/1971 | SDA 38-17 |
| St. Louis at Washington | 10/17/1971 | WAN 16-13 |
| Pittsburgh at Kansas City | 10/18/1971 | PIA 24-17 |
| Buffalo at San Diego | 10/23/1971 | SDA 34-17 |
| Chicago at Detroit | 10/24/1971 | CHN 28-14 |
| Cincinnati at Oakland | 10/24/1971 | OAA 24-17 |
| Denver at Cleveland | 10/24/1971 | CLA 13-6 |
| Green Bay at Los Angeles | 10/24/1971 | LAN 21-17 |
| Houston at Pittsburgh | 10/24/1971 | HOA 27-24 |
| Miami at New York AFC | 10/24/1971 | MIA 24-20 |
| New England at Dallas | 10/24/1971 | DAN 39-3 |
| New Orleans at Atlanta | 10/24/1971 | NON 17-10 |
| New York NFC at Philadelphia | 10/24/1971 | PHN 34-14 |
| San Francisco at St. Louis | 10/24/1971 | SFN 31-31 |
| Washington at Kansas City | 10/24/1971 | KCA 21-17 |
| Baltimore at Minnesota | 10/25/1971 | MNN 20-0 |
| Atlanta at Cleveland | 10/31/1971 | CLA 24-6 |
| Cincinnati at Houston | 10/31/1971 | CNA 24-17 |
| Dallas at Chicago | 10/31/1971 | DAN 21-3 |
| Denver at Philadelphia | 10/31/1971 | DEA 21-13 |
| Kansas City at Oakland | 10/31/1971 | OAA 24-17 |
| Miami at Los Angeles | 10/31/1971 | MIA 27-18 |
| Minnesota at New York NFC | 10/31/1971 | MNN 20-14 |
| New England at San Francisco | 10/31/1971 | NEA 31-6 |
| New Orleans at Washington | 10/31/1971 | NON 25-10 |
| New York AFC at San Diego | 10/31/1971 | SDA 20-3 |
| Pittsburgh at Baltimore | 10/31/1971 | BAA 29-6 |
| St. Louis at Buffalo | 10/31/1971 | BUA 21-20 |
| Detroit at Green Bay | 11/1/1971 | DEN 20-14 |
| Atlanta at Cincinnati | 11/7/1971 | ATN 20-13 |
| Buffalo at Miami | 11/7/1971 | MIA 30-13 |
| Cleveland at Pittsburgh | 11/7/1971 | CLA 28-9 |
| Dallas at St. Louis | 11/7/1971 | DAN 34-14 |
| Detroit at Denver | 11/7/1971 | DEN 34-34 |
| Green Bay at Chicago | 11/7/1971 | GBN 17-17 |
| Houston at New England | 11/7/1971 | HOA 19-10 |
| Kansas City at New York AFC | 11/7/1971 | KCA 26-10 |
| Oakland at New Orleans | 11/7/1971 | NON 34-24 |
| Philadelphia at Washington | 11/7/1971 | WAN 38-3 |
| San Diego at New York NFC | 11/7/1971 | SDA 20-16 |
| San Francisco at Minnesota | 11/7/1971 | MNN 25-17 |
| Los Angeles at Baltimore | 11/8/1971 | BAA 20-17 |
| Baltimore at New York AFC | 11/14/1971 | BAA 13-7 |
| Buffalo at New England | 11/14/1971 | BUA 26-24 |
| Cincinnati at Denver | 11/14/1971 | CNA 24-17 |
| Cleveland at Kansas City | 11/14/1971 | KCA 10-0 |
| Green Bay at Minnesota | 11/14/1971 | MNN 16-7 |
| Houston at Oakland | 11/14/1971 | OAA 37-6 |
| New Orleans at San Francisco | 11/14/1971 | NON 22-0 |
| New York NFC at Atlanta | 11/14/1971 | NYN 24-24 |
| Philadelphia at Dallas | 11/14/1971 | DAN 28-3 |
| Pittsburgh at Miami | 11/14/1971 | MIA 28-3 |
| Los Angeles at Detroit | 11/14/1971 | DEN 20-17 |
| Washington at Chicago | 11/14/1971 | WAN 52-0 |
| St. Louis at San Diego | 11/15/1971 | SDA 29-20 |
| Baltimore at Miami | 11/21/1971 | BAA 23-21 |
| Dallas at Washington | 11/21/1971 | DAN 14-10 |
| Denver at Kansas City | 11/21/1971 | KCA 21-14 |
| Detroit at Chicago | 11/21/1971 | DEN 20-3 |
| Houston at Cincinnati | 11/21/1971 | CNA 13-11 |
| Minnesota at New Orleans | 11/21/1971 | NON 22-9 |
| New England at Cleveland | 11/21/1971 | NEA 24-24 |
| New York NFC at Pittsburgh | 11/21/1971 | PIA 23-16 |
| New York AFC at Buffalo | 11/21/1971 | BUA 24-19 |
| Philadelphia at St. Louis | 11/21/1971 | PHN 21-14 |
| San Diego at Oakland | 11/21/1971 | OAA 41-17 |
| San Francisco at Los Angeles | 11/21/1971 | LAN 23-21 |
| Green Bay at Atlanta | 11/22/1971 | GBN 30-10 |
| Kansas City at Detroit | 11/25/1971 | KCA 17-17 |
| Los Angeles at Dallas | 11/25/1971 | LAN 27-7 |
| Atlanta at Minnesota | 11/28/1971 | ATN 17-7 |
| Baltimore at Oakland | 11/28/1971 | OAA 26-14 |
| Cleveland at Houston | 11/28/1971 | CLA 31-10 |
| Denver at Pittsburgh | 11/28/1971 | PIA 28-23 |
| New England at Buffalo | 11/28/1971 | NEA 23-3 |
| New Orleans at Green Bay | 11/28/1971 | NON 27-0 |
| San Diego at Cincinnati | 11/28/1971 | SDA 34-14 |
| San Francisco at New York AFC | 11/28/1971 | SFN 17-9 |
| St. Louis at New York NFC | 11/28/1971 | SLN 26-7 |
| Washington at Philadelphia | 11/28/1971 | WAN 28-17 |
| Chicago at Miami | 11/29/1971 | MIA 38-10 |
| New York AFC at Dallas | 12/4/1971 | DAN 30-7 |
| Buffalo at Baltimore | 12/5/1971 | BAA 28-27 |
| Chicago at Denver | 12/5/1971 | DEA 20-10 |
| Cincinnati at Cleveland | 12/5/1971 | CLA 17-10 |
| Green Bay at St. Louis | 12/5/1971 | GBN 28-21 |
| Miami at New England | 12/5/1971 | MIA 42-24 |
| Minnesota at San Diego | 12/5/1971 | MNN 28-28 |
| New Orleans at Los Angeles | 12/5/1971 | LAN 28-20 |
| New York NFC at Washington | 12/5/1971 | NYN 16-13 |
| Oakland at Atlanta | 12/5/1971 | OAA 34-10 |
| Philadelphia at Detroit | 12/5/1971 | DEN 24-21 |
| Pittsburgh at Houston | 12/5/1971 | PIA 21-17 |
| Kansas City at San Francisco | 12/6/1971 | SFN 28-16 |
| Detroit at Minnesota | 12/11/1971 | MNN 19-10 |
| Miami at Baltimore | 12/11/1971 | MIA 31-24 |
| Atlanta at San Francisco | 12/12/1971 | SFN 23-17 |
| Chicago at Green Bay | 12/12/1971 | CHN 3-3 |
| Cleveland at New Orleans | 12/12/1971 | CLA 24-13 |
| Dallas at New York NFC | 12/12/1971 | DAN 34-27 |
| Denver at San Diego | 12/12/1971 | SDA 28-17 |
| Houston at Buffalo | 12/12/1971 | HOA 10-10 |
| New England at New York AFC | 12/12/1971 | NYA 28-20 |
| Oakland at Kansas City | 12/12/1971 | OAA 17-12 |
| Pittsburgh at Cincinnati | 12/12/1971 | PIA 22-13 |
| St. Louis at Philadelphia | 12/12/1971 | PHN 38-24 |
| Washington at Los Angeles | 12/13/1971 | LAN 21-13 |
| St. Louis at Dallas | 12/18/1971 | DAN 16-10 |
| Atlanta at New Orleans | 12/19/1971 | NON 26-22 |
| Buffalo at Kansas City | 12/19/1971 | KCA 34-7 |
| Cincinnati at New York AFC | 12/19/1971 | CNA 33-21 |
| Cleveland at Washington | 12/19/1971 | WAN 41-7 |
| Denver at Oakland | 12/19/1971 | DEA 20-6 |
| Detroit at San Francisco | 12/19/1971 | SFN 24-10 |
| Green Bay at Miami | 12/19/1971 | MIA 19-10 |
| Minnesota at Chicago | 12/19/1971 | CHN 10-3 |
| New England at Baltimore | 12/19/1971 | BAA 34-16 |
| Philadelphia at New York NFC | 12/19/1971 | NYN 20-19 |
| Los Angeles at Pittsburgh | 12/19/1971 | LAN 7-3 |
| San Diego at Houston | 12/19/1971 | HOA 24-20 |